منابع مشابه
A New In-Situ Gel Formulation of Itraconazole for Vaginal Administration
In this paper, mucoadhesive in-situ gel with poloxamer and hydroxypropylmethylcellulose formulations of itraconazole were prepared for vaginal application. In addition, rheological, mechanical and mucoadhesive properties and syringeability of the formulations were characterized. The mixtures of Poloxamer 407 and 188 with two different types of hydroxypropylmethylcellulose were used as polymers ...
متن کاملFormulation Development and Evaluation of in Situ Gel for Vaginal Drug Delivery of Anti Fungal Drug
The aim of the present study was to formulate and evaluate nystatin containing thermosensitive mucoadhesive gel for vaginal drug delivery to achieve prolonging the residence time, sustained drug release, enhancing efficacy, decreasing recurrence, and increasing patient compliance in the treatment for vaginal candidiasis. Here nystatin (1%) as a model drug. A 3 full factorial design was employed...
متن کاملChitosan gel containing polymeric nanocapsules: a new formulation for vaginal drug delivery
The vaginal route of administration is an alternative for several treatments for either local or systemic pharmacological effects. However, the permanence of a drug in this route represents a challenge for formulation development that can be overcome by using nanoencapsulation and chitosan gel. Thus, this work aimed to evaluate the performance of chitosan hydrogels containing cationic and anion...
متن کاملFormulation of a poly herbal gel for uterus flux
Background and objectives: Over the centuries, herbal drugs have been used as major sources of medicine for the prevention and treatment of diseases. In recent years, there has been an exponential growth in the field of herbal medicines and these drugs are gaining popularity both in developing and developed countries because of their natural origin and less side effects. The pr...
متن کاملThe effect of itraconazole on treatment of vaginal candidiasis
candidiasis is one of the commonest causes of vaginitis.different treatment have been suggested for this disease.oral itraconazole is one of the newest medications.to evaluate the antifungal activity of this drug in vaginal candidiasis,this study was performed on a random sample of patients.fifty patients with vaginal candidiasis confirmed by direct examination and culture,were treated by a si...
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ژورنال
عنوان ژورنال: Pharmacology & Pharmacy
سال: 2012
ISSN: 2157-9423,2157-9431
DOI: 10.4236/pp.2012.34056